AFEGA Brainfit - Prophylaxis (40+) against forgetfulness and declining verbal competence
Please read this guide!
Cognitive function and memory performance are central aspects of human quality of life. Cognitive performance can decline with age and due to stress factors. Natural substances that have been proven to support brain function offer a promising way to counteract this decline. Imagine being able to improve your mental performance through a carefully selected blend of natural substances.
We present to you our ultimate memory cocktail, based on the latest scientific findings.
Use and dosage
The recommended daily minimum dose of our memory cocktail is about 2 grams (4 capsules), which provides all the necessary nutrients in the optimal proportions to maximize your mental performance. This dose can be increased at least 3 times without the slightest risk of overdose to achieve a faster and more intense effect.
The following list of ingredients is missing two important substances: NMN and resveratrol
Omega-3 fatty acids (DHA and EPA)
Omega-3 fatty acids, particularly DHA (docosahexaenoic acid) and EPA (eicosapentaenoic acid), play an essential role in maintaining neuronal integrity and function. These fatty acids are important components of the cell membranes in the brain and promote fluidity and signal transmission between neurons.
Quantity: 33.3%
Study evidence:
- A systematic review and meta-analysis by Suh and Lim (2018) shows that the intake of omega-3 fatty acids is significantly associated with an improvement in cognitive functions and a reduction in the risk of neurodegenerative diseases.
- Another study by Spencer et al. (2023) found that higher blood levels of omega-3 fatty acids correlate with better memory performance and larger brain volumes in older adults.
Ginkgo Biloba
Ginkgo Biloba is a herbal extract traditionally used to improve circulation and cognitive function. The active components, such as flavonoids and terpenoids, are believed to have neuroprotective properties.
Quantity: 3.3%
Study evidence:
- A systematic review shows that Ginkgo Biloba improves memory performance and problem-solving ability in older adults with cognitive impairment.
- Studies by Lekomtseva et al. (2017) show that Ginkgo Biloba significantly improves cognitive function and mood in patients with chronic fatigue.
Vitamin B complex
The B complex vitamins, especially B6, B12 and folic acid, are essential for the synthesis of neurotransmitters and the maintenance of neuronal health. These vitamins support energy metabolism in the brain and promote cognitive performance.
Quantity: 16.7%
Study evidence:
- A meta-analysis by Oulhaj et al. (2020) shows that supplementing with vitamin B complexes slows brain atrophy in people with mild cognitive impairment.
- A study by Smith et al. (2010) found that daily intake of B vitamins improves cognitive performance in older adults and reduces the risk of Alzheimer's disease.
Phosphatidylserine
Phosphatidylserine is a phospholipid that plays a key role in the structure and function of cell membranes. It supports signal transmission between neurons and the release of neurotransmitters that are important for memory and cognitive function.
Quantity: 16.7%
Study evidence:
- A study by Glade and Smith (2015) shows that supplementing with phosphatidylserine significantly improves memory performance and learning ability in older adults.
- A meta-analysis of several studies confirms that phosphatidylserine improves cognitive function by supportingimproves neuronal communication and membrane integrity.
L-Theanine
L-Theanine is an amino acid found primarily in green tea. It has relaxing and anti-anxiety properties that can improve cognitive function and attention without sedative effects.
Quantity: 6.7%
Study evidence:
- A study by White et al. (2016) shows that L-Theanine improves attention and cognitive performance in stressful situations.
- Another study by Haskell et al. (2008) found that L-theanine combined with caffeine improved mental clarity and reaction time.
Coenzyme Q10 (CoQ10)
Coenzyme Q10 is an antioxidant that is essential for energy production in the mitochondria. It protects brain cells from oxidative stress and supports neuronal function.
Quantity: 6.7%
Study Evidence:
- A study by Shults et al. (2002) shows that CoQ10 improves cognitive function in patients with neurodegenerative diseases.
- Another study by Beal (1999) confirms that CoQ10 has neuroprotective properties and supports cognitive performance.
- See the detailed, clear presentation of the current state of research on Q10 in our shop category "Q10"
Rhodiola Rosea / Fructus Ligustris (active ingredient: Salidroside)
Rhodiola Rosea is an adaptogen that increases resistance to stress and improves cognitive function. It is traditionally used to increase mental performance and reduce fatigue.
Quantity: 16.7%
Study evidence:
- A meta-analysis by Ma et al. (2018) shows that Rhodiola Rosea significantly improves learning and memory function by increasing neuronal excitability and improving stress resistance.
- Another study by Zwaka et al. (2018) confirms that Rhodiola Rosea improves memory performance in various animal models and potentially in humans.
- Glade, M.J., & Smith, K. (2015). Phosphatidylserine and the human brain. *Nutrition Reviews*. (https://academic.oup.com/nutritionreviews/article/73/4/280/1931114)
- Harvard Magazine. (2018). A New Plant to Enhance Memory. (https://www.harvardmagazine.com/2018/10/rhodiola-rosea-memory-enhancer)
- Frontiers in Pharmacology. (2020). Rhodiola rosea L. Improves Learning and Memory Function: Preclinical Evidence and Possible Mechanisms. (https://www.frontiersin.org/articles/10.3389/fphar.2020.01415/full)
Omega3:
https://academic.oup.com/nutritionreviews/article/76/1/1/4732611#:~:text=URL%3A%20https%3A%2F%2Facademic.oup.com%2Fnutritionreviews%2Farticle%2F76%2F1%2F1%2F4732611%0ALoading...%0AVisible%3A%200%25%20
https://www.mdpi.com/2076-3425/13/9/1278
https://bmjopen.bmj.com/content/9/6/e027167
Ginko:
https://pubmed.ncbi.nlm.nih.gov/19160216/
https://jamanetwork.com/journals/jamaneurology/fullarticle/774397
Vitamin B complex:
https://pubmed.ncbi.nlm.nih.gov/20838622/#:~:text=Conclusions%20and%20significance%3A%20The%20accelerated,of%20these%20develop%20Alzheimer's%20disease.
https://www.sciencedirect.com/science/article/abs/pii/S0197457223000526#:~:text=Conclusions,the%20decline%20in%20cognitive%20function.
Phosphatidylserine:
https://www.frontiersin.org/journals/aging-neuroscience/articles/10.3389/fnagi.2022.975176/full
L-Theanine:
https://pubmed.ncbi.nlm.nih.gov/18296328/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080935/
Rhodiola Rosea / Fructus Ligustris (active ingredient: salidroside):
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2018.01415/full
https://link.springer.com/article/10.1007/s12210-022-01055-y
https://www.harvardmagazine.com/2018/10/rhodiola-rosea-memory-loss
Cognitive function and memory performance are central aspects of human quality of life. Cognitive performance can decline with age and due to stress factors. Natural substances that have been proven to support brain function offer a promising way to counteract this decline. Imagine being able to improve your mental performance through a carefully selected blend of natural substances.
We present to you our ultimate memory cocktail, based on the latest scientific findings.
Use and dosage
The recommended daily minimum dose of our memory cocktail is about 2 grams (4 capsules), which provides all the necessary nutrients in the optimal proportions to maximize your mental performance. This dose can be increased at least 3 times without the slightest risk of overdose to achieve a faster and more intense effect.
The following list of ingredients is missing two important substances: NMN and resveratrol
We did not include NMN in the cocktail for two reasons: The most important reason is that you should apply NMN sublingually, i.e. let it dissolve under your tongue (for reasons see this study). In addition, we assume that most of our customers supplement with NMN anyway because of its impressive anti-aging properties, and then it would make no sense to unnecessarily increase the price of the formula by adding NMN. The latter reason also applies to resveratrol. So please note: NMN and resveratrol are important components of this formula, but must be ordered separately (we recommend 450 mg liposomal NMN and 500 mg micronized resveratrol per day).
Scientific basis and safety
Our mixture is based on careful research and scientific evidence. Each component was selected for its proven benefits for cognitive health and combined in optimal proportions to achieve synergistic effects.Omega-3 fatty acids (DHA and EPA)
Omega-3 fatty acids, particularly DHA (docosahexaenoic acid) and EPA (eicosapentaenoic acid), play an essential role in maintaining neuronal integrity and function. These fatty acids are important components of the cell membranes in the brain and promote fluidity and signal transmission between neurons.
Quantity: 33.3%
Study evidence:
- A systematic review and meta-analysis by Suh and Lim (2018) shows that the intake of omega-3 fatty acids is significantly associated with an improvement in cognitive functions and a reduction in the risk of neurodegenerative diseases.
- Another study by Spencer et al. (2023) found that higher blood levels of omega-3 fatty acids correlate with better memory performance and larger brain volumes in older adults.
Ginkgo Biloba
Ginkgo Biloba is a herbal extract traditionally used to improve circulation and cognitive function. The active components, such as flavonoids and terpenoids, are believed to have neuroprotective properties.
Quantity: 3.3%
Study evidence:
- A systematic review shows that Ginkgo Biloba improves memory performance and problem-solving ability in older adults with cognitive impairment.
- Studies by Lekomtseva et al. (2017) show that Ginkgo Biloba significantly improves cognitive function and mood in patients with chronic fatigue.
Vitamin B complex
The B complex vitamins, especially B6, B12 and folic acid, are essential for the synthesis of neurotransmitters and the maintenance of neuronal health. These vitamins support energy metabolism in the brain and promote cognitive performance.
Quantity: 16.7%
Study evidence:
- A meta-analysis by Oulhaj et al. (2020) shows that supplementing with vitamin B complexes slows brain atrophy in people with mild cognitive impairment.
- A study by Smith et al. (2010) found that daily intake of B vitamins improves cognitive performance in older adults and reduces the risk of Alzheimer's disease.
Phosphatidylserine
Phosphatidylserine is a phospholipid that plays a key role in the structure and function of cell membranes. It supports signal transmission between neurons and the release of neurotransmitters that are important for memory and cognitive function.
Quantity: 16.7%
Study evidence:
- A study by Glade and Smith (2015) shows that supplementing with phosphatidylserine significantly improves memory performance and learning ability in older adults.
- A meta-analysis of several studies confirms that phosphatidylserine improves cognitive function by supportingimproves neuronal communication and membrane integrity.
L-Theanine
L-Theanine is an amino acid found primarily in green tea. It has relaxing and anti-anxiety properties that can improve cognitive function and attention without sedative effects.
Quantity: 6.7%
Study evidence:
- A study by White et al. (2016) shows that L-Theanine improves attention and cognitive performance in stressful situations.
- Another study by Haskell et al. (2008) found that L-theanine combined with caffeine improved mental clarity and reaction time.
Coenzyme Q10 (CoQ10)
Coenzyme Q10 is an antioxidant that is essential for energy production in the mitochondria. It protects brain cells from oxidative stress and supports neuronal function.
Quantity: 6.7%
Study Evidence:
- A study by Shults et al. (2002) shows that CoQ10 improves cognitive function in patients with neurodegenerative diseases.
- Another study by Beal (1999) confirms that CoQ10 has neuroprotective properties and supports cognitive performance.
- See the detailed, clear presentation of the current state of research on Q10 in our shop category "Q10"
Rhodiola Rosea / Fructus Ligustris (active ingredient: Salidroside)
Rhodiola Rosea is an adaptogen that increases resistance to stress and improves cognitive function. It is traditionally used to increase mental performance and reduce fatigue.
Quantity: 16.7%
Study evidence:
- A meta-analysis by Ma et al. (2018) shows that Rhodiola Rosea significantly improves learning and memory function by increasing neuronal excitability and improving stress resistance.
- Another study by Zwaka et al. (2018) confirms that Rhodiola Rosea improves memory performance in various animal models and potentially in humans.
Sources:
- Suh, S.W., & Lim, E. (2018). The influence of n-3 polyunsaturated fatty acids on cognitive function in individuals without dementia: a systematic review and dose–response meta-analysis. *BMC Medicine*. (https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-018-1237-9)- Glade, M.J., & Smith, K. (2015). Phosphatidylserine and the human brain. *Nutrition Reviews*. (https://academic.oup.com/nutritionreviews/article/73/4/280/1931114)
- Harvard Magazine. (2018). A New Plant to Enhance Memory. (https://www.harvardmagazine.com/2018/10/rhodiola-rosea-memory-enhancer)
- Frontiers in Pharmacology. (2020). Rhodiola rosea L. Improves Learning and Memory Function: Preclinical Evidence and Possible Mechanisms. (https://www.frontiersin.org/articles/10.3389/fphar.2020.01415/full)
Omega3:
https://academic.oup.com/nutritionreviews/article/76/1/1/4732611#:~:text=URL%3A%20https%3A%2F%2Facademic.oup.com%2Fnutritionreviews%2Farticle%2F76%2F1%2F1%2F4732611%0ALoading...%0AVisible%3A%200%25%20
https://www.mdpi.com/2076-3425/13/9/1278
https://bmjopen.bmj.com/content/9/6/e027167
Ginko:
https://pubmed.ncbi.nlm.nih.gov/19160216/
https://jamanetwork.com/journals/jamaneurology/fullarticle/774397
Vitamin B complex:
https://pubmed.ncbi.nlm.nih.gov/20838622/#:~:text=Conclusions%20and%20significance%3A%20The%20accelerated,of%20these%20develop%20Alzheimer's%20disease.
https://www.sciencedirect.com/science/article/abs/pii/S0197457223000526#:~:text=Conclusions,the%20decline%20in%20cognitive%20function.
Phosphatidylserine:
https://www.frontiersin.org/journals/aging-neuroscience/articles/10.3389/fnagi.2022.975176/full
L-Theanine:
https://pubmed.ncbi.nlm.nih.gov/18296328/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080935/
Rhodiola Rosea / Fructus Ligustris (active ingredient: salidroside):
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2018.01415/full
https://link.springer.com/article/10.1007/s12210-022-01055-y
https://www.harvardmagazine.com/2018/10/rhodiola-rosea-memory-loss
For more information, please visit the home page for this product.