250g NMN powder, purity > 99%, CAS 1094-61-7
Storage: Shelf life of at least 2 years when stored in the refrigerator
Liposomal NMN (nicotinamide mononucleotide) from Natural Field offers several advantages that set it apart from conventional NMN products:
1. Increased bioavailability: Liposomal encapsulation allows NMN to be better absorbed by the body. Liposomes are tiny fat particles that envelop and protect the active ingredients, allowing them to be transported into the cells more efficiently[1][2].2. Improved stability:Liposomal formulations protect NMN from degradation by gastric acid and enzymes in the digestive tract, increasing the stability and effectiveness of the active ingredient[1].
3. Targeted delivery:Liposomes can deliver the active ingredients specifically to the cells, improving the efficiency of the treatment and maximizing the desired health benefits[1].
4. Longer duration of action: The gradual release of the active ingredient from the liposomes allows for a longer duration of action, resulting in a more sustained effect[1].
These benefits make Natural Field's liposomal NMN an effective option for those who want to maximize the health benefits of NMN.
Citations:
[1] https://de.nfnatural.com/info/liposomes-benefits-in-natural-field-94878995.html
[2] https://natural-field.com/de/liposomales-NNM-Superpulver.html
The effectiveness of liposomal NMN is confirmed by several scientific studies that demonstrate the benefits of this special dosage form highlight:
1. Increased bioavailability and efficiency:
- Dr. Christopher W. Shade explains that liposomal NMN has a higher absorption rate and efficiency compared to conventional capsules. The liposomes protect NMN from degradation in the digestive tract and enable faster and more efficient absorption into the body[1].
- A study shows that liposomal formulations can improve the distribution of NMN in the body and deliver the active ingredients specifically to the cells, increasing the efficiency of the treatment[4].
2. Improved stability and protection:
- Liposomal NMN formulations protect the active ingredient from degradation by gastric acid and enzymes, increasing the stability and effectiveness of the NMN[1][2].
- NMN remains stable in liposomal form and is efficiently converted to NAD+, which is critical for cellular health and anti-aging effects[2].
3. Clinical studies and health benefits:
- Studies in mice have shown that NMN offers a variety of health benefits, including improving energy metabolism, increasing insulin sensitivity, and improving mitochondrial function[2][3].
- First-in-human clinical trials, such as those from Keio University and Harvard University, show promising results regarding the safety and efficacy of NMN. These studies suggest that NMN may improve metabolic health and alleviate age-related health problems[3].
4. Specific Health Uses:
- Dr. Shade highlights that liposomal NMN is particularly beneficial for cardiometabolic health, including controlling blood sugar levels and improving insulin sensitivity[1].
- NMN has also shown neuroprotective effects by improving distribution to the brain and alleviating neurodegenerative diseases[4].
Citations:
[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238906/
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238909/
[3] https://www.nature.com/articles/d42473-022-00002-7
[4] https://www.sciencedirect.com/science/article/pii/S2324242624000184
Is sublingual administration (letting the powder dissolve under the tongue) also necessary or beneficial for liposomal NMN?
Sublingual administration of liposomal NMN is not as necessary/useful as for regular NMN, as the liposomes already protect the NMN from degradation in the liver and gastrointestinal tract. The liposomal formulation has the advantage that the NMN molecules are encapsulated in liposomes (lipid bilayers). This prevents premature degradation of the NMN and enables more efficient absorption into the bloodstream.
We recommend sublingual administration for regular NMN because studies show that this significantly increases bioavailability by bypassing degradation in the liver[1]. However, with liposomal NMN, this advantage is no longer as relevant, as the liposomes already protect the NMN from degradation. However, since the liposomal NMN we offer is suitable for sublingual application, you may still have an additional advantage with sublingual application. However, there are currently no study results that reliably prove this.
Sources:
[1] https://www.cell.com/cell-metabolism/pdfExtended/S1550-4131(18)30196-7